Grounded in your evidence
Every response draws on EV evidence records, ranked entities, and source-backed provenance from the active result — nothing is fabricated or inferred from outside your search.
EVd3x v1
beta
Search any miRNA, mRNA, or protein — EVd3x maps it across EV evidence, pathways, disease, and cell context in one workspace.
Direct launches
Natural-language launches
After Analyze
You found your molecules. Now understand what they mean.
EVd3x moves you from a list of cargo hits to testable biological insight in four steps — each grounded in EV-specific evidence, not generic enrichment.
01
Measure cargo signal
Quantify EV-supported evidence for every molecule — direct database records, inferred associations, and source-level provenance.
02
Map biological relevance
Connect cargo to pathways, diseases, cell types, and interaction networks from the active graph — not from a separate tool.
03
Manipulate analysis state
Pivot across analysis views, adjust filters, and reshape top-N windows to stress-test hypotheses before committing to bench work.
04
Validate experimentally
Export prioritized candidates with full evidence tables and graph context — structured for targeted validation planning.
Agentic Framework
An AI assistant grounded in your loaded data
The assistant reasons from your active graph, summary state, and analysis tabs — never from outside the loaded context. It routes you to the right surface and explains what it finds.
Routes to the right analysis
Ask a question in natural language and the assistant opens the relevant module — pathway, disease, cell context, L-R, or PPI — with the right filters applied.
Helps you narrow, not just explore
It reshapes top-N lists, adjusts subsets, and structures exports so your hypotheses are experiment-ready — all within browser-safe compute limits.
Coverage snapshot
What EVd3x covers today
Evidence, pathway, interaction, and disease layers unified in a single graph-native workspace.
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Integrated Databases
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Canonical Molecules
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EV Evidence Rows
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Publications Indexed
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Pathway Memberships
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Disease Associations
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miRNA-Gene Targets
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Ligand-Receptor Pairs
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STRING Interactions
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Expression Profiles
Analysis Surface
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Node-level and system-level views spanning EV Evidence, Pathway, Disease, Cell Context, L-R, and PPI modules.
Interactive Graph Views
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Search-aware layouts with legends, fit controls, and direct navigation into analysis tabs from the same workspace.
Research Exports
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Publication-ready tables, figure assets, graph bundles, and CSV exports with full provenance metadata.
Core analysis modules
Six modules that turn cargo lists into biological insight
Every module operates on your active graph and summary state. Switch tabs freely — the loaded context follows you.
EV Evidence
See which databases support each molecule, drill into provenance rows, filter by sample type, and trace back to EV-TRACK-linked studies.
Pathway
Run enrichment across integrated pathway sources and connect your cargo to biological programs — not isolated gene lists.
Disease
Surface direct and predicted disease associations with publication-backed evidence and ranked system-level summaries.
Cell Context
Identify the most relevant cell types for your cargo and use cell-level context as the starting point for communication analysis.
L-R Analysis
Project ligand-receptor pairs from your active system using relevance-ranked starter sets designed to run efficiently in the browser.
PPI + Exports
Expand proteins into STRING interaction neighborhoods, inspect context, and export figures or data tables without leaving your analysis.
Grounding and provenance
Every result traces back to its source
Canonical identifiers, database provenance, and publication-linked records stay attached across summaries, tabs, and exports — so nothing loses its origin.
EV Evidence
Pathway Databases
Ligand-Receptor Atlas
STRING PPI
Cell Expression
Data connectivity
Canonical IDs link molecules across pathway, interaction, and disease layers in a single connected graph.
Evidence granularity
Every analysis tab preserves source-level rows with publication and database provenance intact.
Processing transparency
Display caps keep views responsive; exports include the full candidate set when available.
Analysis Workspace
Single Cargo Analysis
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Node Details Overview
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Ranking cell types...
Cell Context
Cell Specificity
Cell Specificity Table
Localization Readiness Table
Preparing communication view
Review selected source cells, then click Update Communication to apply changes.
Running analysis...
Cell Communication
Selected Source Cells
Source → Target Cell Interactions
Interaction Details
System flow overview
Top Interacting Cell Pairs
Analyzing ligands & receptors...
Running enrichment analysis...
Pathway Enrichment
Top Enriched Pathways
Biological Themes Overview
Scored Pathway Results
Analyzing disease associations...
Disease Associations
Priority Diseases
Disease Themes
Disease Evidence Explorer
Click to select. Click again to clear. Drag to reposition. Use fit/reset to navigate.
